ヒトにおける選択反応時間課題:ラットと同等な手続きにおける検討

概要

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Animal models of human behavioral or cognitive processes are essential for studying mechanisms of these processes. A choice reaction time task was developed for assessing sustained attention in rats; a previous study showed that rats perform the task as predicted from other sustained attention tasks in rats and humans. In this study, we measured the behavior of humans in a choice reaction time task procedurally matched to the task for rats, and examined the effect of decreasing the presentation rate of stimulus through prolonging the inter-trial intervals, which was previously shown to affect performance in rats. As in rats, choice reaction speed decreased and omission errors increased as the decrease of presentation rate of stimulus. These data showed that choice reaction time behavior both in rats and humans was controlled similarly by the parameter, which suggests that this task assesses similar processes of sustained attention in the two species.