A Case of Isoniazid-Induced Thrombocytopenia: Recovery with Immunoglobulin Therapy
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概要
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Treatment for a 51-year-old man with pulmonary tuberculosis was initiated with isoniazid, rifampicin, ethambutol, and pyrazinamide, and discontinued after 3 weeks because of skin rash and itchiness. Isoniazid monotherapy was restarted after 2 weeks. Two days later, the platelet count decreased from 150 to 4×103/mm3. Despite platelet transfusion and oral corticosteroid treatment, the platelet count did not recover. However, after a 2-day administration of intravenous immunoglobulin, the platelet count recovered to 209×103/mm3. This report describes a case of isoniazid-induced thrombocytopenia that was reversed with intravenous immunoglobulin, thus highlighting the efficacy of this treatment for this rare condition.
著者
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JU Lee
Department of Materials Science & Engineering, Faculty of Engineering, Kyushu University
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Yeong Jeong
Department of Internal Medicine, College of Medicine, Gyeongsang National University, Korea
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Hun Lee
Department of Internal Medicine, College of Medicine, Gyeongsang National University, Korea
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Eun Kim
Department of Internal Medicine, College of Medicine, Gyeongsang National University, Korea
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Jun Lee
Department of Internal Medicine, College of Medicine, Gyeongsang National University, Korea
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Ji Cho
Department of Internal Medicine, College of Medicine, Gyeongsang National University, Korea
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Cheol Kim
Department of Internal Medicine, College of Medicine, Gyeongsang National University, Korea
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Deog Lee
Department of Internal Medicine, College of Medicine, Gyeongsang National University, Korea
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Sil Hwang
Department of Internal Medicine, College of Medicine, Gyeongsang National University, Korea
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Ju Lee
Department of Internal Medicine, College of Medicine, Gyeongsang National University, Korea
関連論文
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- A Case of Isoniazid-Induced Thrombocytopenia: Recovery with Immunoglobulin Therapy