Evaluation of the Carbon Dioxide-balneotherapy on the Microcirculation and Oxygen Tension in Peripheral Arterial Occlusive Disease.

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概要

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• The effects of immersion of the lower leg and foot in fresh water and in CO2-enriched water (1200mg CO2 per kg water; succinate+sodium bicarbonate: Kao-BubR) on cutaneous circulation, vasomotion and oxygen tension (PO2) were measured by laser Doppler flowmetry and transcutaneous oximetry. On the first of two consecutive days patients were randomly assigned to have the lower extremities immersed in either fresh water or CO2-enriched water under standardised conditions (temperature, 34°C; depth, 35cm; immersion time, 20min) with concurrent measurement. On the second day patients were switched to the other bath type. For both sets of measurements probes were attached symmetrically to the dorsum of each foot. 18 patients with mild, bilateral, peripheral, occlusive arterial disease (intermittent claudication, femoral or iliac type) were included in the study.During immersion in CO2-enriched water the Doppler laser signal and vasomotion amplitude rose by 300%, while PO2 increased by 10%. These increases were still apparent during the latter part of the measurement period, following withdrawal of the limbs from the bath, while patients were seated and supine. During immersion in fresh water and thereafter the Doppler laser signal was unchanged and the PO2 increase was considerably less marked.We were thus able to demonstrate vasodilation and increased oxygen utilisation (Bohr effect) resulting from topical CO2 application, and hence that the use of topical CO2 has an objective basis.

• 一般社団法人 日本温泉気候物理医学会の論文

著者

• DREWS B.

  Institute of Applied Physiology and Balneologie, University Freiburg

• BASSENGE E.

  Institute of Applied Physiology and Balneologie, University Freiburg

• Hartmann B.

  Institut Fur Angewandte Physiologie Und Balneologie Der A-l-universitat Freiburg

• Hartmann B.

  Institute of Applied Physiology and Balneology, University of Freiburg i. Br., Department of Health Resort Therapy

• Burnus C.

  Institute of Applied Physiology and Balneology, University of Freiburg i. Br., Department of Health Resort Therapy

• Bassenge E.

  Institute of Applied Physiology and Balneology, University of Freiburg i. Br., Department of Health Resort Therapy

関連論文

• Venous Function in Patients with Venous Disease and Healthy Controls before and after a Bathing Procedure and Subsequent Cold Stimulus
• Physical Therapy Improves Venous Haemodynamics in Cases of Primary Varicosity: Results of a controlled study
• Evaluation of the Carbon Dioxide-balneotherapy on the Microcirculation and Oxygen Tension in Peripheral Arterial Occlusive Disease.

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