Evaluation of Efficacy of Treatment with an Absorbing Markov Chain Model
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概要
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In general, the efficacy of any medical treatment will be evaluated from the observation of the time course of symptoms which patients will present in response to the treatment.<BR>After employing an appropriate model of an absorbing Markov chain, these time series data can be submitted to a statistical analysis.<BR>In the model, a patient is represented as a stochastic system. Then the time process of the reactivity of the system to the treatment is examined in terms of its transition probability.<BR>In the present paper, the validity of the method in studying the transitional pattern of the state of patient was investigated in the case of treatment of purpura.<BR>The method with the model above mentioned proved to be of advantage in judging statistically the efficacy of the treatment.
- 一般社団法人 日本臨床薬理学会の論文