ELECTRICAL ACTIVITY OF THE GUINEA-PIG SEMINAL VESICLE AND THE EFFECTS OF AUTONOMIC AGENTS <I>IN SITU</I>

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概要

• 論文の詳細を見る

• Studies were made of effects of hypogastric nerve stimulation on the electrical activity of guinea-pig seminal vesicle with extracellular silver microelectrodes <I>in situ</I>. Furthermore, the effects of several autonomic agents were also investigated. Junction potentials with facilitation were observed during repetitive stimulation of the hypogastric nerve, which were affected by intravenous administration of reserpine, bretylium tosylate, guanethidine, hexamethonium and pentolinium. On the other hand, atropine and α-blocking agents had no detectable effects. Intravenous administration of noradrenaline leads to periodic bursts of spike discharges accompanied with the contraction of seminal vesicle. The results suggested that seminal vesicle of guinea-pig may be innervated by hypogastric nerve such fashion as was deferens.

• 日本平滑筋学会の論文

著者

• 武田 寛

  塩野義製薬

• 武田 寛

  塩野義製薬株式会社研究所

• 中西 弘則

  塩野義製薬株式会社研究所

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