Experimental studies on hepatic circulation : Effects of some drugs on blood flows in liver tissue and portal vein of the cats.:EFFECTS OF SOME DRUGS ON BLOOD FLOWS IN LIVER TISSUE AND PORTAL VEIN OF THE CATS

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概要

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• The effects of some drugs on the hepatic circulation were examined by thermoelectrical and electromagnetic methods under pentobarbital-anesthesia in normal and CCl<SUB>4</SUB>-pretreated cats.<BR>The following results were obtained.<BR>1. Both adrenergic α and β receptor functions were involved in the regulation of the hepatic circulation of normal cats.<BR>2. Three calcium blockers (nifedipine, nicardipine, diltiazem) had different potencies in increasing the hepatic blood flow of normal cats.<BR>3. The isolated veins including portal vein showed the regional difference in the responsiveness to calcium blockers.<BR>4. In CCl<SUB>4</SUB>-pretreated cats, adrenergic α receptor function was dominant in the control of hepatic circulation and diltiazem raised portal venous pressure.

• 日本平滑筋学会の論文

著者

• 大宮 安紀彦

  千葉大学医学部第二外科学教室

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• Experimental studies on hepatic circulation : Effects of some drugs on blood flows in liver tissue and portal vein of the cats.:EFFECTS OF SOME DRUGS ON BLOOD FLOWS IN LIVER TISSUE AND PORTAL VEIN OF THE CATS

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