ELECTROPHYSIOLOGICAL STUDIES ON THE PERISTALTIC PROPAGATION IN THE INTESTINAL BLIND POUCH

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To clarify the basic conduction pattern of the anastomosed intestine with a blind pouch, the author performed the experiments, in which the action potential was recorded from the blind loop developed following a sideto-side anastomosis after resection of rabbit's intestine and the motile function of the loop was observed.<BR>The electrodes were placed at four different sites and the whole preparation was immersed in Tyrode solution.<BR>1. Dilatation and hypertrophy of the blind loop were progressive, and diarrhea, weight loss, malnutrition and dehydration were aggravated in time.<BR>2. Over more than three months after blind loop formation, iso-peristaltic propagation is seen in a caudal direction and anti-peristaltic conduction from blind end to the entrance of the loop, causing collision of both peristaltic waves. The amplitude of spikes recorded from the distal site was apparently increased.<BR>3. In view of the fact that a side-to-side anastomosis may cause blind pouch formation, the superiority of an end-to-end anastomosis over a side-toside anastomosi s is suggested.
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