EFFECT OF LOCAL DISTENSION OF THE STOMACH ON THE MOTOR FUNCTION OF THE PYLORUS

概要

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The present study deals with the effect of local distension of the stomach on the motor function of the pyloric portion. The experiment was undertaken with canine stomachs. A. rubber balloon was introduced into the stomach. And, by inflating the balloon with air. fnn.dus, body and pyloric region of the stomach was distended individually. The results are summarized as follows:<BR>1) When the same amount of air was introduced, excitation of the pyloric portion was most evident by the distension of pyloric region followed by the distension of the body and the fundus.<BR>2) Gradual over-distension of any region of the stomach resulted in excitation of the peristaltic movement which was most remarkable in the pyloric region associated with frequent occurrence of anti-peristalsis.<BR>These findings suggest that the abnormal excitation of the pyloric portion may be caused by severe gastric retention followed by an increase in intraluminal pressure of the stomach, particularly of the pyloric portion.