EFFECTS OF ANTIPERISTALTIC ILEAL SEGMENT ON INTESTINAL MOTILITY IN SUBTOTAL COLECTOMIZED DOGS
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Experimentally, 60 mongorel dogs were subjected to subtotal colectomy with addition of a 5 cm reversed segment of terminal ileum, which was interposed between the small bowel and the residual rectal cuff.<BR>Following these animals for 6 monthes after surgery, they showed no remarkable difference of body weight, total serum proteins concentration, or hematocrit value, compared with the control group which were anastomosed isoperistaltically.<BR>The addition of a 5 cm reversed intestinal segment prolonged mouth-to-anus transit time, and was very effective for shortening the recovery from diarrhea.<BR>Electrical activity was recorded from the immediate cranial portion (portion A), and caudal portion (portion B) of the upper anastomosis and the immediate cranial portion (portion C) of the ileoproctostomy.<BR>In company with portion A, both portion B and portion C showed electrophysiologically chronic hypertrophic changes in 24 weeks postoperatively. No propagation of movement beyond the upper anastomotic line was observed.<BR>In the reversed ileal segment, peristalsis maintained original direction up to 24weeks after surgery in electrophysiological studies and X-ray cinematographic observations of bowel motility.<BR>From observation of X-ray cinematography and the removed specimens, it was supposed that the 5 cm reversed ileal segment was usefull as a reservoir portion after loss of reservoir function of the colon.<BR>The clinical application of an antiperistaltic segment of adequate length for patients requiring colectomy would appear feasible.
- 日本平滑筋学会の論文
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- EFFECTS OF ANTIPERISTALTIC ILEAL SEGMENT ON INTESTINAL MOTILITY IN SUBTOTAL COLECTOMIZED DOGS