Epilepsies Beginning at Less Than Four Years of Age: The Application of the International Classification of Epilepsies and Epileptic Syndromes.:The Application of the International Classification of Epilepsies and Epileptic Syndromes

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We classified 95 patients (49 boys, 46 girls) with epilepsies that began at less than four years of age, according to the International Classification of Epilepsies and Epileptic Syndromes (ICE). In 55.8% of all patients, the onset was before one year of age. Localization-related epilepsies were observed in 73.7% of patients, generalized epilepsies in 23.2%, and 2.1% were undetermined whether focal or generalized. Very few patients had idiopathic epilepsies, namely, only 5.3% of all patients manifested idiopathic generalized epilepsies. Symptomatic localization-related epilepsies were more common among the patients with seizures beginning at between three and four years of age. On the other hand, symptomatic generalized epilepsies were morecommon in the younger group, especially among the patients with seizures beginning at less than one year of age. The onset of all seven patients who showed evolutional change to other type of epilepsies was under one year of age. Their transition was related to West syndrome or EME. We could classify 99% of all patients with ICE. This fact proved the usefulness of ICE in infancy. However, only 40% of patients were classifiable into epileptic syndromes. In particular, syndrome classification was difficult in localization-related epilepsies.
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