A Case of Heard-Word-Induced Epilepsy

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A three-year-five-month old boy, with severe mental retardation and epilepsy caused as sequelae of acute encephalopathy, manifested a peculiar type of reflex epilepsy. He started to have only spontaneous atonic seizures at three years four months of age. Later, the same kind of atonic seizures began to be induced by hearing the specific words besides spontaneous seizures. At first, reflex seizures were induced exclusively by hearing the word "terebi", which means a television, but triggering words gradually expanded to not only "terebi" but also "tehpu", tape, and "te", hand, and finally to any words with the sound of "te".<BR>The type of seizures both spontaneous and evoked, were atonic seizures. It was suggested that not only brainstem but also cerebral cortex played important roles in the provocation mechanism of heard-word-induced seizures, since the latency of beginning of desynchronization of EEG from the start of verbal stimulus was longer than 480 msec.<BR>Conditioning treatment with the tape, in which the word "terebi" was recorded repeatedly, was found to be effective for the evoked seizures by hearing the specific word "terebi".
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