Structures of yadanziosides K, M, N, and O, new quassinoid glycosides from Brucea javanica (L.) Merr.

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概要

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• Four new bitter quassinoid glycosides, yadanziosides K, M, N, and O were isolated from <I>Brucea javanica</I> (L.) MERR and their structures were determined by spectral measurement and chemical means. The aglycone of yadanzioside O was found to exhibit a significant antitumor activity against the murine P388 lymphocytic leukemia and this aglycone could be prepared from brusatol.

著者

• Sakaki Toshiro

  Department of Chemistry, Faculty of Science, The University of Tokyo

関連論文

• Structures of yadanziosides K, M, N, and O, new quassinoid glycosides from Brucea javanica (L.) Merr.
• Structures of new quassinoid glycosides, yadanziosides A,B,C,D,E,G,H, and new quassinoids, dehydrobrusatol and dehydrobruceantinol from Brucea javanica (L.) Merr.
• Constituents of seeds of Brucea javanica. Structures of new bitter principles, yadanziolides A,B,C, yadanziosides F,I,J, and L.

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