Reaction of nitrosyl chloride gas with unsaturated steroids.

スポンサーリンク

概要

• 論文の詳細を見る

• Reaction of nitrosyl chloride gas at 0 °C with 3,5-cholestadiene (<B>1</B>) provided 3,6β-dinitro-5-chloro-5α-cholest-3-ene (<B>4</B>) and with 3α,5-cyclo-5α-cholestan-6-one (<B>2</B>) afforded 3β-chloro-5-nitro-5α-cholestan-6-one (<B>7</B>) and 3β-chloro-6-nitrato-5-cholestene (<B>8</B>). Similar reaction with 6-hydroxylimino 3α,5-cyclo-5α-cholestane (<B>3</B>) gave 3β,6-dichloro-5-cholestene (<B>10</B>), 3β-chloro-6-nitratoimino-5α-cholestane (<B>11</B>) and 3β,5-dichloro-6-nitroimino-5β-cholestane (<B>12</B>). Compound <B>12</B> upon hydrolysis furnished 3β,5-dichloro-5β-cholestan-6-one (<B>14</B>). The structures of these compounds were established on the basis of their spectral properties, and some pertinent chemical transformations. Mechanisms for the formation of some unusual products are discussed.

• 公益社団法人 日本化学会の論文

著者

• Rafiuddin Ansari

  Department of Chemistry, Aligarh Muslim University

• Husain Shakir

  Department of Chemistry, Aligarh Muslim University

関連論文

• Reaction of nitrosyl chloride gas with unsaturated steroids.

スポンサーリンク