Synthesis and application of some 1-(8-hydroxy-5(or 7)-quinolinyl)-alkylidene-substituted heterocycles as bactericides, funjicides, and bioregulator.

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概要

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• Interaction of 5-acetyl-8-quinolinol, corresponding 1-ethylquinolinium iodides, and 8-hydroxyquinoline-7-carbaldehyde with diethylmalonate under basic condition gave the corresponding of <B>4</B>–<B>6</B>. Further reaction of <B>4</B>–<B>6</B> with hydrazine, phenyl hydrazine, hydroxylamine, urea, and/or thiourea gave the corresponding 1-[8-hydroxy-5(7)-quinolinyl]alkylidene-substituted heterocyclic derivatives (<B>7</B>–<B>16</B>) and corresponding 1-ethylquinolinium iodides (<B>17</B>–<B>21</B>). The structure of the synthesized compounds was confirmed by elemental and spectral analysis. The biological activity of 5-substituted 8-quinolinol was tested as microbicidal and bioregulator agents, the results obtained were interpreted according to their structure-activity relationships.

• 公益社団法人 日本化学会の論文

著者

• Khalil Zarif

  Chemistry Department, Faculty of Science, Assiut University

• Yanni Amal

  Chemistry Department, Faculty of Science, Assiut University

• Khalaf Ali

  Chemistry Department, Faculty of Science, Assiut University

• Abdel-Hafez Ali

  Chemistry Department, Faculty of Science, Assiut University

• Abdo Raafat

  Chemistry Department, Faculty of Science, Assiut University

関連論文

• Synthesis of merocyanine dyes.
• Synthesis and application of some 1-(8-hydroxy-5(or 7)-quinolinyl)-alkylidene-substituted heterocycles as bactericides, funjicides, and bioregulator.

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