Synthetic study on peptide antibiotic nisin. IV. Synthesis of ring D-E.

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概要

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• In the series of synthetic study on peptide antibiotic nisin, a bicyclic sulfide part ring D–E in this molecule was successfully synthesized. Conjunctive sulfide rings were constructed either by one step or stepwise desulfurization reaction from corresponding disulfides by use of hexaethylphosphorus triamide. Thus, all of the ring moieties in nisin were prepared for total synthesis of this antibiotic.

• 公益社団法人 日本化学会の論文

著者

• Oda Yoshiaki

  Department of Chemistry, Faculty of Science, Osaka University

関連論文

• Synthetic study on peptide antibiotic nisin. IV. Synthesis of ring D-E.

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