Nitriles in heterocyclic synthesis. Synthesis and reactions of pyrano(3,2-h)quinoline derivatives.
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概要
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8-Quinolinol reacts with cinnamonitrile derivatives in presence of a basic catalyst to afford pyrano[3,2-<I>h</I>]quinolines (<B>3a–f</B>). The reaction of <B>3a</B> with reagents such as acetic anhydride/pyridine, formamide, formic acid/formamide, and carbon disulfide gave the fused heterotetracyclic systems pyrimido[4′,5′: 6,5]pyrano[3,2-<I>h</I>]quinolines.
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著者
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Kamal El-Dean
Chemistry Department, Faculty of Science, Assiut University
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Abdel-Hafez A.
Chemistry Department, Faculty of Science, Assiut University
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Khalil Z.
Chemistry Department, Faculty of Science, Assiut University
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Geies A.
Chemistry Department, Faculty of Science, Assiut University