Mechanisms of Agglomeration of Red Cells by High Polymer Compounds
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概要
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The mechanisms of agglomeration of erythrocytes caused by hydrophilic negative polymers were investigated and the following views were proposed.<BR>(1) Among the negative colloids, fibrous colloids show the erythrocyte agglomeration, while spherical ones do not cause it.<BR>(2) Agglomeration by the negative colloids is caused by two actions, i. e., adsorption of these polymers upon cells and their action to join cells together. Those substances which lack either or both of these actions fail to cause the agglomeration.<BR>(3) Fibrous structure of macromolecule favors these actions on account of the large extension of molecule and adequate flexibility of each part of the molecule in solution.<BR>(4) The dissociated or dipol radicals of the negative polymers and amino groups of the protein of cell surface are considered to be the centres of adsorption respectively.
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