The Dehydrating Cyclization of <I>S</I>-Carboxymethyl-cysteine and <I>N</I>-Acetyl-<I>S</I>-carboxymethyl-cysteine
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概要
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<I>S</I>-Carboxymethyl-cysteine (SCMC) cyclizes by dehydration to form 3-oxo-5-carboxy-per-hydro-1,4-thiazine (SCMC-lactam) when the aqueous solution was heated at 110∼180°C. SCMC-lactam was also obtained from <I>N</I>-acetyl-SCMC when the latter was treated with <I>N</I>,<I>N</I>′-dicyclohexylcarbodiimide and hydrolyzed subsequently at pH 9.0.
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