Studies on Antibiotics and Related Substances. XIII. Syntheses of 10-Methylene-11-oxododecanoic Acid and 9-Methylene-10-oxoundecanoic Acid, Antitumor Substances
スポンサーリンク
概要
- 論文の詳細を見る
1) 10-(Dimethylaminomethyl) -11-oxododecanoic acid hydrochloride (Ia) and 9-(dimethylaminomethyl) -10-oxoundecanoic acid (Ib) have been obtained from the mother liquors remaining after filtration of 13-(dimethylamino)-11-oxotridecanoic acid hydrochloride and 12-(dimethylamino)-10-oxododecanoic acid hydrochloride, respectively.<BR>2) 10-Methylene-11-oxododecanoic acid (IVa) and 9-methylene-10-oxoundecanoic acid (IVb) have been synthesized from the Mannich bases Ia and Ib, respectively.<BR>3) Antitumor activities of IVa and IVb have been described.
- 社団法人 日本化学会の論文
著者
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Umezawa Sumio
Department of Applied Chemistry Faculty of Engineering Keio University
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Kinoshita M.
Department of Chemistry Faculty of Science The University of Tokyo
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Nakada Saburo
Department of Applied Chemistry Faculty of Engineering Keio Univerity
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Nakada Saburo
Department of Applied Chemistry Faculty of Engineering Keio University
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Kinoshita Mitsuhiro
Department of Applied Chemistry Faculty of Engineering Keio University
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