ROLE OF CALCIUM IN DRUG ACTION ON SMOOTH MUSCLE
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概要
- 論文の詳細を見る
1. Calcium is essential for the stimulating action of ACh, serotonin, histamine and oxytocin on smooth muscle, both in normal Ringer and K-Ringer.<BR>2. In contrast with the above drugs, barium does not require the presence of calcium in Ringer or K-Ringer for its stimulatory action. Calcium rather depresses the barium effect.<BR>3. These phenomena are discussed in relation to a concept that calcium and barium act directly on contractile protein of smooth muscle.
- 公益社団法人 日本薬理学会の論文
著者
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EBASHI FUMIKO
Department of Pharmacology, Faculty of Medicine, University of Tokyo
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Yukisada N.
Department of Pharmacology, Faculty of Medicine, University of Tokyo