72. 脳動脈瘤術後血管攣縮に対するATP持続投与の試み

概要

論文の詳細を見る
Adenosine triphosphate (ATP) was used in 15 cases of ruptured intracranial aneurysm soon after the aneurysm was clipped in order to reduce the vasospasm. ATP was given in 40mg at first, then maintained in 100mg daily for 4 days to 22 days by continuous intravenous injection. In other 15 operative cases ATP was not used as a control. The frequency and the quantity of vasospasm was studied correlated with CAG findings, postoperative courses and CT findings. In ATP group the vasospasm was less frequent, the degree of vasospasm was mild and the postoperative course was more favorable in spite of the severe subarachnoid hemorrhage in CT finding in comparison with non-ATP group. The continuous administration of ATP will have good effect when ATP is used in addition to the conventional treatment for cerebral vasospasm after subarachnoid hemorrhage.
The Japanese Society on Surgery for Cerebral Strokeの論文