Xenotropic Murine Leukemia Virus-Related Virus Proviral DNA Not Detected in Blood Samples Donated in Japan

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概要

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• The xenotropic murine leukemia virus-related virus (XMRV) was first described as a novel human gammaretrovirus in prostate tumor tissues and was reported to be found in blood, suggesting the possibility of XMRV transmission via blood transfusion. The gag and env regions of the XMRV proviral DNA that were detected in 1,030 blood samples collected from the greater Tokyo area were examined by real-time PCR analysis. However, XMRV infection was not found in the samples; this suggested that the risk of XMRV transmission via transfusion is very low in Japan.

著者

• Tadokoro Kenji

  Japanese Red Cross Central Blood Center

• SATAKE Masahiro

  Japanese Red Cross Society Blood Service Headquarters

• Matsumoto Chieko

  Japanese Red Cross Society Blood Service Headquarters

• Tadokoro Kenji

  Japanese Red Cross Society Blood Service Headquarters

• Igarashi Masashi

  Japanese Red Cross Society Blood Service Headquarters

• Uchida Shigeharu

  Japanese Red Cross Society Blood Service Headquarters

• Furuta Rika

  Japanese Red Cross Kinki Block Blood Center

関連論文

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• Intra- and inter-laboratory variability in human T-cell leukemia virus type-1 proviral load quantification using real-time polymerase chain reaction assays : A multi-center study
• Xenotropic Murine Leukemia Virus-Related Virus Proviral DNA Not Detected in Blood Samples Donated in Japan

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