エストロゲンと脂質代謝:III エストロゲンのコレステロール代謝に及ぼす影響について
スポンサーリンク
概要
- 論文の詳細を見る
Cholesterol-4-C<SUP>14</SUP> was intravenously injected into a number of rats each of which was receiving daily injections of 50μg. of estradiol benzoate, and the radioactivity of their serum and faeces were measured for ten days. The results obtained were as follows. <BR>1) The total cholesterol, the cholesterol ester fraction and the free cholesterol fraction of the treated animals had lower radioactivity than those of the controls, and the difference grew more and more conspicuous with the lapse of time. <BR>2) The rats treated with estradiol for 15 days had clearly lower values of total serum cholesterol, cholesterol ester, and free cholesterol than the controls. <BR>3) The radioactivity of the total faeces, and the neutral sterol and the bile acid fractions were higher in the rats receiving estradiol than in the controls. <BR>4) Estradiol was found to promote the degradation and excretion of cholesterol-4-C<SUP>14</SUP> intravenously injected to rats.
- 日本内分泌学会の論文