甲状腺疾患に関する研究 (第2報):Cortisol代謝におよぼす甲状腺ホルモンの影響

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概要

• 論文の詳細を見る

• The influence of thyroid hormone on secretory activity of adrenal cortex and cortisol metabolism was studied clinically and experimtntally.<BR>Base levels of plasma cortisol were within normal range regardless of thyroid functions in 6 hyper-Rate of clearance of cortisol from the body was accelerated by thyroid hormone either in reduction and conjugation by human liver or in renal clearance of guinea pigs.<BR>Hyperactivity of adrenal cortex in hyperthyroidism, and diminished adrenal activity in myxedema, seem to be an expression of feed back mechanism of anterior pituitary to maintain a constant plasma level of cortisol as suggested previouly by DiRaimondo, Peterson and other investigator. There was some evidence of exhaustion in secretory activity of adrenal cortex in hyperthyroidism due to over doses of ACTH stimulation.

• 日本内分泌学会の論文

著者

• 武部 和夫

  北海道大学医学部第二内科

関連論文

• 23. 気管支喘息の下垂体副腎機能(第14回日本アレルギー学会総会)
• 甲状腺疾患に関する研究 (第2報):Cortisol代謝におよぼす甲状腺ホルモンの影響

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