Androgen及びEstrogenの協力作用について

概要

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(1) By means of seminal vesicles and prostata weighing test (Fevold), we investigated the co-operative functions of androgen and estrogen mixture agents day by day. By changing their ratio and dosis, some interesting results were obtained. Maximum co-operative effects were observed under following conditions : i.e. By 5 mg. and 2.5mg., testosterone to estrogen ratio was 30 to l. By 1.25mg., the ratio was 20 to l. (2) According to the rise of estrogen level, the peak of maximum effects shifted to the right and aslo became uneffective. As above mentioned, when the androgenic effects were wanted in administration of mixture hormone, estrogen ratio to androgen might not be too great.
日本内分泌学会の論文