放射性同位元素I131による甲状腺機能亢進症の治療について

概要

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The result of treatment with 27-434 μc/g of radioisotop I131 on hyperthyroidism is as follows. On first administration, 88.8% of male and 91.8% of female healed. Including, however, second administration the result reversed, namely, greater number of female result in healing than male. Both P. B. I. and B. M. R. reduced proportionately to after adminisration of I131. Before institution, comparing a up-take value of 1 hr with of 24 hrs, first one showing more close relation than later. This relationship becomes rather rough after administration. Vit. C in blood is extremely high or low before administration, but this returned to normal level after. In relationship between total protein and I131 no significance obtained. Of electropholetic analysis of protein, however, the amount of γ-globulin increased after I131 given. These above observation lead us to the conclusion, that in order to make exact diagnosis of Hyperthyroidism not one, but several test should be carried out simultaneously.
日本内分泌学会の論文