Severe Inhibition of in Vitro Cardiomyogenesis in Mouse Embryonic Stem Cells Ectopically Expressing EGAM1C Homeoprotein
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概要
- 論文の詳細を見る
Embryoid bodies were prepared from mouse embryonic stem cells expressing exogenous EGAM1C to analyze their ability to differentiate toward terminally differentiated cell types. The generation of cardiomyocytes was severely suppressed in Egam1c transfectants without upregulation of Nkx2-5, a crucial gene for cardiomyogenesis. These results indicate that EGAM1C is capable of affecting terminal differentiation in mouse embryonic stem cells.
- Japan Society for Bioscience, Biotechnology, and Agrochemistryの論文
著者
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Sakaki Shujiro
Applied Chemistry Department Akita National College Of Technology
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Mori Yuki
Laboratory Of Soil Science Division Of Soil Science And Plant Production Department Of Plant Resourc
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Yamada Satoshi
Tsukuba Research Laboratory Nof Corporation
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Kasuga Kano
Laboratory For Biological Chemistry Graduate School Of Bioresource Sciences Akita Prefectural Univer
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Kobayashi Masayuki
Laboratory For Advanced Animal Cell Technology Graduate School Of Bioresource Sciences Akita Prefect
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Kojima Ikuo
Laboratory For Biological Chemistry Graduate School Of Bioresource Sciences Akita Prefectural Univer
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IHA Momoe
Laboratory for Advanced Animal Cell Technology, Graduate School of Bioresource Sciences, Akita Prefectural University
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SOMA Miki
Laboratory for Advanced Animal Cell Technology, Graduate School of Bioresource Sciences, Akita Prefectural University
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SATO Sho
Laboratory for Advanced Animal Cell Technology, Graduate School of Bioresource Sciences, Akita Prefectural University
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SUGAWARA Saiko
Laboratory for Advanced Animal Cell Technology, Graduate School of Bioresource Sciences, Akita Prefectural University
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Soma Miki
Laboratory For Advanced Animal Cell Technology Graduate School Of Bioresource Sciences Akita Prefectural University
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Sugawara Saiko
Laboratory For Advanced Animal Cell Technology Graduate School Of Bioresource Sciences Akita Prefectural University
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Iha Momoe
Laboratory For Advanced Animal Cell Technology Graduate School Of Bioresource Sciences Akita Prefectural University
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Mori Yuki
Laboratory For Advanced Animal Cell Technology Graduate School Of Bioresource Sciences Akita Prefectural University
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Yamada Satoshi
Tsukuba Corporate Research Laboratory Nof Corporation
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Kojima Ikuo
Laboratory for Biological Chemistry, Graduate School of Bioresource Sciences, Akita Prefectural University
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Mori Yuki
Laboratory for Advanced Animal Cell Technology, Graduate School of Bioresource Sciences, Akita Prefectural University
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