A New Cyclic Tetrapeptide from the Jellyfish-Derived Fungus Phoma sp.
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概要
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A new cyclic tetrapeptide (1), along with known congeners (2, 3), was isolated from the fungus Phoma sp. derived from the giant jellyfish Nemopilema nomurai. The absolute configuration of 1 was determined using the modified Mosher’s method and Marfey’s method. Compound 1 displayed a weak suppressive effect on the production of nitric oxide (NO) in murine macrophage cells (RAW264.7) without notable cytotoxicity.
著者
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Li Jian
College of Pharmacy, Pusan National University
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Jung Jee
College Of Pharmacy Pusan National University
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Hong Jongki
College Of Pharmacy Kyung Hee University
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Kim Eun
College of Oriental Medicine and Institute of Oriental Medicine, Kyung Hee University
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Kim Eun
College of Pharmacy, Pusan National University
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Xiao Bin
College of Pharmacy, Pusan National University
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Yoo Eun
School of Medicine, Jeju National University
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Yoon Won
National Fisheries Research and Development Institute
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