Synthesis and Pharmacological Profile of a New Selective G Protein-Coupled Receptor 119 Agonist; 6-((2-Fluoro-3-(1-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-yl)propyl)amino)-2,3-dihydro-1H-inden-1-one

スポンサーリンク

概要

• 論文の詳細を見る

• 6-((2-Fluoro-3-(1-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-yl)propyl)amino)-2,3-dihydro-1H-inden-1-one is a potent drug-like G protein-coupled receptor 119 (GPR119) agonist. It is hoped that this compound would be instrumental in probing the pharmacological potential of GPR119 agonists.

著者

• Takahashi Naoki

  Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd.

• Torii Masafumi

  Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd.

• Sakairi Masao

  Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd.

• Kogami Masakazu

  Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd.

• Makino Mitsuhiro

  Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd.

• Kataoka Daisuke

  Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd.

• Okamoto Ryuji

  Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd.

• Miyazawa Toshiyuki

  Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd.

• Inoue Megumi

  Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd.

• Harada Satoko

  Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd.

• Watanabe Nobuhide

  Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho Co., Ltd.

関連論文

• Practical Preparation of Ethyl 2-Methylthiophene-3-carboxylate
• Synthesis and Pharmacological Profile of a New Selective G Protein-Coupled Receptor 119 Agonist; 6-((2-Fluoro-3-(1-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-yl)propyl)amino)-2,3-dihydro-1H-inden-1-one

スポンサーリンク