Furandiones from an Endophytic Aspergillus terreus Residing in Malus halliana

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概要

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• Two new furandiones named asperterone B (1) and C (2) together with four known metabolites (3–6) were isolated from the liquid culture of the endophytic fungus Aspergillus terreus MHL-P22 residing in the fresh leaves of Malus halliana. The structures of the new compounds were elucidated by analysis of their MS, IR, 1D- and 2D-NMR spectra. 1 and 2 showed moderate cytotoxic activities against human colorectal carcinoma SW1116 cells with IC50 values of 57.5 and 71.0 µM, respectively. The biosynthetic pathway for 1, 2 and their analogues was also postulated and briefly discussed.

著者

• Gu Wen

  College of Chemical Engineering, Nanjing Forestry University

• Qiao Chao

  College of Chemical Engineering, Nanjing Forestry University

関連論文

• Furandiones from an Endophytic Aspergillus terreus Residing in Malus halliana

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