Enantioselective Synthesis of 8-epi-Xanthatin and Biological Evaluation of Xanthanolides and Their Derivatives
スポンサーリンク
概要
- 論文の詳細を見る
An enantioselective synthesis of 8-epi-xanthatin (9) has been accomplished starting from the bicyclic lactone 3, which has been used for the synthesis of other xanthanolides, sundiversifolide (4) and diversifolide (5), through a synthetic route without the use of a selenium species. Additionally we have evaluated antimicrobial activities of five natural xanthanolides and their derivatives. Although the synthetic xanthanolides did not show any activity against methicillin-resistant Staphylococcus aureus (MRSA), some of the synthetic intermediates did exhibit moderate antimicrobial activities.
著者
-
Shishido Kozo
Graduate School Of Pharmaceutical Sciences The University Of Tokushima
-
Shibata Hirofumi
Graduate School Of Pharmaceutical Sciences University Of Tokushima
-
Manabe Yuki
Graduate School Of Information Science And Technology Osaka University
-
Yoshida Masahiro
Graduate School Of Pharmaceutical Sciences The University Of Tokushima
-
Yoshida Masahiro
Graduate School of Pharmaceutical Sciences, The University of Tokushima
-
Yokoe Hiromasa
Graduate School of Pharmaceutical Sciences, The University of Tokushima
-
Noboru Kentaro
Graduate School of Pharmaceutical Sciences, The University of Tokushima
-
Shibata Hirofumi
Graduate School of Pharmaceutical Sciences, The University of Tokushima
-
Manabe Yuki
Graduate School of Pharmaceutical Sciences, The University of Tokushima
関連論文
- A Protocol for Real-Time Remote Musical Session(Cyberworlds)
- Chemical Constituents of Capsicum annuum L var. angulosum, and Anti Helicobacter pylori Activity
- A Prototype of Comparison Tool for Android Applications Based on Difference of API Calling Sequences
- Chemical Constituents of Capsicum annuum L var. angulosum, and Anti Helicobacter pylori Activity
- P-19 SYNTHETIC STUDIES ON THIOMARINOL B
- Enantioselective Synthesis of 8-epi-Xanthatin and Biological Evaluation of Xanthanolides and Their Derivatives
- Development of Palladium-Catalyzed Transformations Using Propargylic Compounds
- Towards Logging Optimization for Dynamic Object Process Graph Construction
- Semi-Automatically Extracting Features from Source Code of Android Applications
- Total Synthesis of Aspergillides Using a Transannular Oxy-Michael Strategy