Gelatine修飾液による血液稀釈が循環及び酸塩基平衡へ及ぼす影響
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概要
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We discussed the effects on the circulation and acid base balance of the dog when elective haemodilution is done with the use of gelatine haemaccel solution, which is colloidal solution. There is an increase in cardiac output and decrease in total protein when gelatine haemaccel solvent just as Lactate Ringer's solution, Dextran, or Hydroxyethyl starch is used. The amount of gelatine haemaccel solution which transfuses to maintain the circulation was 1.2 times as much as the blood removed.<BR>When we dilute the hematocrit down to ten per cent, the martality rate increased and the metabolic acidosis progressed.<BR>Therefore, we should consider that the critical point for dilution of hematocrit is from twenty to twenty-five per cent.<BR>Retransfusing the blood after hemodilution, the circulatory system will normalize ; however, the recovery of hemoglobin and hematocrit was not sufficient.
- 学校法人 昭和大学・昭和医学会の論文