成人動脈壁厚の年齢的変化について
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概要
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The wall thickness of 34 arteries from 152 human adults (male: 71, female: 81) was measured and the age-related changes were examined. The materials used in this study were obtained from autopsy subjects in the Tokyo Metropolitan Medical Examiner Office and were examined in the non-fixed condition.<BR>1) Wall thickness was generally larger on large caliber arteries than on small caliber arteries. As an exception, the wall thickness of A. mesenterica superior was larger than that of other arteries with the same caliber.<BR>2) The wall thickness of arteries increased with age for all parts of the aorta and for proximal parts of lower extremity arteries. It did not increase on arteries of the peripheral parts of lower extremities or in the abdominal cavity. It was greatest at 40-70 years old on the arteries in the cervical region and in the upper extremities.<BR>3) The ratio of wall thickness to inner circumference was larger in small arteries than in large arteries.<BR>4) The thickness to circumference ratio in male subjects increased with age for all parts of the aorta, A. iliaca communis and the arteries in the cervical region and the upper extremities. In the lower extremities and the abdominal cavity, it temporarily decreased during a ten year span with the minima occurring at age 40 to 60, depending on the artery. On the other hand, in females the thickness to circumference ratio increased with age on the arteries in the cervical region, decreased with age on the all parts of the aorta, and the temporary decreases occurred between the ages of 40 and 60 on other arteries.<BR>5) From this data and previous data on inner circumference growth with age, it was concluded that the decrease in thickness to circumference ratio is a result of circumference increase without accompanying wall growth.<BR>6) In the relationship between wall thickness and inner circumference, the larger thickness of artery wall is accompanied by larger circumference of most arteries examined in the female, but this tendency was seen only on the aorta in the male, while other arteries in the male showed a large tendency of the wall thickness to increase with age and little tendency of the inner circumference to change.
- 学校法人 昭和大学・昭和医学会の論文