新生児の病理組織学的研究--特に低体重出生児を中心とした胎盤について
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概要
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From the comparative study of patho-histological investigation into the relations of SFD to AFD and LFD fetal placentas, especially in the case of SFD fetal placenta where placental factors are most significant, we have concluded as follows:<BR>(1) SFD, AFD and LFD placentas all increase both in volume and weight with the progress of pregnancy between 28 and 32 weeks. An arrested development of SFD fetal placenta is observed, however, starting between 33 and 35 weeks and a tendency of SFD AFD LFD is shown in 33 weeks of fetal age and thereafter, increase the weight differences as the fetal age advances.<BR>(2) Mutual relations in placental ratio are found in the order of SFD, AFD, LFD in 33 weeks and thereafter. It is also observed that the ratio decreases as the fetal age increases.<BR>(3) The fetal placenta of SFD fetus from placental factors is more highly occupied by the profundus chorionic blood vessels and the VSM formation is suppressed as compared with those of SFD fetus from maternal factors or of AFD and LFD fetuses.<BR>(4) Fibrosis of villus stroma occurs in the chorionic region among the chorionic stem and branches and some of the villi from earlier stages in the placenta of SFD fetus from fetal factors than in other cases such as SFD fetus from maternal factors, AFD and LFD fetuses.<BR>(5) Patho-morphological observations described in (3) and (4) compose the two main characteristics in the fetal placenta of SFD fetus from placental factors.<BR>(6) Observations in (3) and (4) are both considered to be patho-morphologically serious as the obstructional factors of blood vessels causing functional disorder between the mother and the fetus.<BR>(7) We have conjectured from the above observations that the high occupancy by the profundus chorionic blood vessels, a suppressed VSM formation and an early fibrosis of villus stroma in the placenta of SFD fetus from placental factors are closely related to the delay of prenatal development.
- 学校法人 昭和大学・昭和医学会の論文