溶血性物質による肝臓融解性壊死についての病理学的検討
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概要
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Zonal necrosis frequently occurs when the liver is subjected to a severe toxic stress. Though coagulation necrosis usually occurs under such circumstances, colliquative necrosis in a small number of cases should not be overlooked. A pathological study was therefore undertaken on the process in the liver from colliquative changes to colliquative necrosis in-duced by injecting saponin and hydroxylamin hydrochloride subcutaneously in a rabbit.<BR>Colliquative necrosis was thus produced in radiating form along the sinusoid connect-ing the central and the peripheral vein.<BR>Such colliquative necrosis in the radiation form was probably related to hemolytic anemic hypoxemia induced by hydroxylamin and saponin.
- 学校法人 昭和大学・昭和医学会の論文