吉田皮下腫瘍における移植腫瘍の栄養状態と放射線感受性について
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概要
- 論文の詳細を見る
Studies on radiosensitivity of the tramsplanted tumor were carried out and following results were obtained<BR>1. Radiosensitivity of the tumor ran parallel to the growth rate.<BR>2. Malnutrition of the host after irradiation made the tumor radiosensitive, probably because sublethally damaged tumor cell did not recover.<BR>3. Mitotic index was well correlated to radiosensitivity and low mitotic index caused by starvation made the tumor cell to recover poorly.<BR>4. DNA synthetic rate measured by means of iodine labeled IUdR was not successful to correlate with mitotic rate, presumably because of the role of thymidine pool size in this experiment.<BR>5. Serum protein level was likely to correlate to the tumor growth, which modified the radiosensitivity.<BR>6. Serum oxygen was difficult to interpret, however might be compensated by erythrocytosis in starved condition.
- 学校法人 昭和大学・昭和医学会の論文