尋常性乾癬42例の観察

概要

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Clinical and histopathological observations were performed on 42 cases of psoriasis vulgaris treated in 1965-Feb. 1967. These cases consisted of 25 males and 17 females, of whom 29 cases (69%) were aged 20-50 with highest incidence in the 3rd decade of life and the durations of the disease were within 5 years in 34 cases (81%) . The patients' occupations had no significant connection with the onset of this disease. The extremities were found to be the site of predilection. Serum cholesterol levels examined in 6 cases were within normal limit. In 6 cases histologically examined, the specimens of all cases showed hyperkeratosis, parakeratosis, thinning of the suprapapillary portions of the Stratum Malpighii, elongation of the rete ridges, edema and capillary dilatation of the papillae and inflammatory infiltrate in the upper dermis, and only 2 cases revealed Munro microabscesses. The occlusive dressing technique with fluocinolone acetonide cream, Goeckerman therapy and the administration with corticosteroid were considerablly effective among various treatments.
学校法人昭和大学・昭和医学会の論文