アスコルビン酸欠乏モルモットの糖代謝について
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概要
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Many studies bring the fact that the synthesis of collagen decline under the condition in the case of scorbutic guinea pigs. They also provide that the same condition have influence on the carbohydrate metabolism. Assuming that a lowering of collagen synthesis under scorbutic guinea pig is owe to that of composition of polysaccharide which is regard to be neccessary for the collagen synthesis, we firstly produced scurvy of symptoms on guinea pigs by scorbutic diet and studied enzymes of carbohydrate metabolism using those livers. Enzymes are phospho-glucomutase, 6-phosphoglucoisomerase, glucose-6-phosphatase, glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase. Of them, a deviation from normality was shown only in glucose-6-phosphate dehydrogenase. Other enzymes did not show so much deviation from normality. Such our study is proved different from that by Ganguli in India which proves they show a large deviation.
- 学校法人 昭和大学・昭和医学会の論文