子宮体癌の増殖形態について
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概要
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The growth patterns at the tip of cancer infiltration were studied in 85 cases of endometrial cancer which were excised by operation.<BR>Generally, the rate of cancer growth is divided into 2 types; the comparatively slow growing type and the rapid growing one. Morphologically, the growth patterns of polypoid forms, superficially spreading forms (mucosa cancer) and expansively or plexif ormlike intramuscularly infiltrated forms, represent the former type. These growth patterns are also seen in benign tumor.<BR>On the other hand, cancer cells scatter intramuscularly into small cell groups and permeate into the lymph-and blood-vessels of myometrium, in the rapid growing type.<BR>The former growth patterns, were 42.3 % of the cases studied. In these cases the cancer localizes to corpus uteri, the degree of intramuscular infiltration is shallow, stroma is fibroplastic or nonreactive, cancer cells consist of differentiated adenocarcinoma and the prognosis is favorable.<BR>In the latter type, the spread of cancer is wide, cancer infiltration often reaches the serosa of the uterus or cervix, stroma is fibrolytic, cancer cells are anaplastic and often have ovarial metastasis and prognosis is unfavorable.
- 学校法人 昭和大学・昭和医学会の論文