銅蛋白Caeruloplasminの肝臓カタラーゼ活性, 鉄, 銅代謝, 組織呼吸に及ぼす影響
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概要
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To investigate the influences of reduced and oxidized caeruloplasmin on the liver metabolism of rats, copper and iron metabolism, catalase activity and tissue respiration were estimated.<BR>Caeruloplasmin were administered to rats repeatedly into their tail veins.<BR>Following results were obtained.<BR>1) The increase of copper level and marked increase of iron level per gram of liver weight were observed in rats administered caeruloplasmin.<BR>2) Catalase activity and tissue respiration of the liver of rats were increased by administration of copper protein.<BR>3) These influences of caeruloplasmin on the liver of rats were greater in its reduced form than in its oxidized form.<BR>The increase of catalase activity, tissue respiration and iron level of rats was observed more markedly when caeruloplasmin was administered for long period.
- 昭和大学・昭和医学会の論文