Salmonella typhiの変異に関する研究-1-

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Several supplementary studies were undertaken on the dwarf (D) type variation of Salmonella typhi. Firstly, D type colony mutants were isolated from Salmonella typhi Ty2 (S type) and the one obtained from V type colony of Ty2 strain was named as dv and that from the W type colony as dw. Findings of the studies made on those variants were as follows : 1. D type colonies of the 24 hour growth were 0.2-1 mm in diameter, while S type colonies had a diameter of ca. 2 mm. In contrast to the latter, the bacilli of the former type colony were rather irregular in size. 2. The variation of S (V) -3dv→S (V) —dv was recognized. 3. The variation of S (W) →dw→S (W) →dw was recognized. 4. The rate of D-S variation showed no difference on varying culture media such as blood agar, various kinds of sugar agar, Endo's agar, and sodiun sulphite agar. 5. All the 4 kinds of colonies possessed similar f ermentability against various kinds of sugars. Acid agglutination and O, H and Vi factor serum agglutination showed the presence of relationship of V type to W type but not to D type or S type. 6. As for their virulence in mice, there will not be a great mistake in regarding that those 4 mutants possess the relationship same as that stated above.
学校法人昭和大学・昭和医学会の論文