2-Methyl-4-amino-5-hydroxymethylpyrimidine痙攣に就いて
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概要
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The spasmolytic effects of OMP, INAH and B1 on the rabbit and mouse were studied.<BR>Features of the spasms appeared were somewhat different depending on the drug administered.. Development of spasms was inhibited more or less by the simultaneous administration of a centrall depressant such as Dilantin, Sulfonal, or Bromural.<BR>When TOED was administered into the cranial cisterna of the rabbit, there appeared the spasms resembling to those caused by B<SUB>1</SUB> administration.<BR>Moreover, when a large dose of B<SUB>6</SUB> was administered on the mouse, spasms appeared, but in this case they were not inhibited by the simultaneous application of OMP. It was found, therefore, the antagonism between OMP and B<SUB>6</SUB> is only for one way.
- 学校法人 昭和大学・昭和医学会の論文
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