螢光抗体法による日本脳炎ウイルス垂直伝播の解析

スポンサーリンク

概要

• 論文の詳細を見る

• JaTH 160 strain of Japanese encephalitis virus was inoculated intraperitoneally into pregnant hamsters. Vertical transmission of viral infection was followed in some animals which inoculated during the first 4 th to 10 th day of pregnancy.<BR>Three to 4 days after infection, immunofluorescent studies showed specific viral antigen in cytoplasm of endothelial cells located in maternal uterine blood vessels. One or two days later, specific antigen appeared in maternal placental tissue. Five to six days after infection, specific fluorescent cells increased in number forming confluent focal lesions. These lesions acted as primary foci in fetus, and the virus infection spread quite rapidly through fetal blood vessels. The infected fetus showed specific antigen in endothelial cells of capillary, cartilage membrane, heart muscles, trunc muscles, dental germs, Auerbach's plexus in gastrointestinal tract, central nervous system, lungs and kidneys.

• 昭和大学・昭和医学会の論文

著者

• 伊東 佑英

  昭和大学医学部小児科学教室

関連論文

• 広汎な拡がりを呈したサルコイドージスの一剖検例
• Fetomaternal transfusionにより高度貧血を呈した一新生児例
• 小児気管支喘息治療における病歴カルテについて
• 螢光抗体法による日本脳炎ウイルス垂直伝播の解析

スポンサーリンク