ストレプトザイムテスト(ヘモプロ-ベSZ)の臨床的意義について

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Serological methods for the diagnosis of group A streptococcal infection have proved to be of considerable importance both to the clinical investigator and to the practicing physician. Currently, most clinical diagnostic laboratories perform only a single streptococcal antibody determination the antistreptolysin O (ASLO) test. Unfortunately, some of habitual angina patients have normal serum titers of ASLO, and these problems may be largely overcome by measuring, in addition to ASLO, serum antibodies to the other known extracellular enzymes of group A streptoccoci. A simple and rapid procedure, capable of sinultaneously detecting serum antibodies to a variety of streptocal extracellular products, would be desirable. The streptozyme test may possibly meet these specifications. In the studies reported here, streptozyme test was compared with a battery of conventional antibody determinations (ASLO, Blue ASO, Latex ASL, ASK-SD, Precipitating antibody to SK-SD) in diagnosis of a variety of streptococcal diseases. The relationship between the streptozyme test and other anti-streptococcal antibody titers was studied. Correlation coefficients between streptozyme test and ASLO, ASK-SD, Blue ASO, Latex ASL and Precipitating antibody to SK-SD were r=0.458, 0.528, 0.442, 0.581, and 0.355, respectively. The results suggest that the streptozyme test may indeed be a useful procedure for routine serological diagnosis of group A streptoccal infection.
耳鼻咽喉科臨床学会の論文

ストレプトザイムテスト(ヘモプロ-ベSZ)の臨床的意義について

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