顔面神経修復術後のmecobalamin長期投与の経験

概要

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Mecobalamin, 1500μg/day, was administered to the eleven patients on whom surgical repair of the facial nerve had been done. On nine patients, eight with Bell's palsy and one with Ramsay Hunt's syndrome, an intratemporal decompression operation was carried out one month or more after the onset. Their palsies were complete and the nerves were proved to be seriously degenerated. On two patients extratemporal facial nerve grafting was performed immediately after removal of the parotid tumor. Administration of mecobalamin continued for more than three months, an average of 27 weeks, after the operation. Comparing with our previous result of operation, we have noted favourable effects on the restoration of the facial nerve function. Although further clinical and experimental verification is needed, this preliminary study has suggested that the drug potentially promotes regeneration of the facial nerve.
耳鼻咽喉科臨床学会の論文