抗ヒスタミン剤Mequitazine(LM-209)の鼻アレルギ-に対する臨床効果

概要

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To evaluate the clinical effect and safety, LM 209 was prescribed for 115 patients with nasal allergy. The results are as follows:1) The effective rate (excellent and good) by doctors' judgement and patient's judgement were 57.0% and 52.8% respectively.2) The improvement of provocative reaction was 46.0% and the decrease of eosinophils in nasal smear was 39.4%.3) The degree each of subjective symptoms were significantly decreased.4) The rate of side-effects was 11.9% and drowsiness was 7.3%, which are very lower than that of other anti-histaminic agents. There was no remarkable abnormal value in the laboratory test.
耳鼻咽喉科臨床学会の論文