小児鼻副鼻腔炎に対するEM少量投与法

概要

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The clinical efficacy of low dose erythromycin (10mg/kg/day) was investigated in 58 children with sinusitis.1. Intranasal findings were completely cleared in 50.0% of patients, improved in 25.9% and unchanged in 24.1%. Follow-up X-ray films of the sinuses showed complete cure of the disease in 13.3%, improvement in 53.3% and no change in 33.3%.2. The shorter the period of infection, the higher was the response rate.3. Patients below 4 years of age showed a much better response to this treatment than did patients above 4 years of age.4. Treatment for two months is recommended for maximum efficacy.5. Mild diarrhea in one patient was the only side effect observed. In conclusion, our data indicate that low dose erythromycin is useful in the treatment of children with sinusitis.
耳鼻咽喉科臨床学会の論文