Experiences with Nutrase in the Treatment of Neural Deafness

概要

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Drug therapies for neural deafness have long been studied in various manners, with no satisfactory outcomes yet. A rigorous fact about the above treatment is that the restoration of hearing functions is beyond hope after the nerve cells have undergone irreversible changes. Adequate treatment, therefore, has to be started and completed while the pathologic changes are still in the functional phase and are reversible.Nutrase with a structural formula of a free-form vitamin B1 which is phosphorylated has recently been administered daily for 21 consecutive days to subjects picked up at random from among the inpatients and outpatients of our Department with neural deafness and also from among the Streptomycin-deaf inmates of the National Oshima Seishoen Leprosarium. Evaluation of the drug effect mainly in terms of improvement in hearing acuteness of bone conduction, found improved hearing acuteness in 27% of the former group of the drug-recipients and in 33% of the latter.We have found Nutrase to be an effective drug for the treatment of neural deafness.
耳鼻咽喉科臨床学会の論文