The effect of hemorrhagic acute anemia on wound healing. Influence of serum transfusion.:Influence of serum transfusion

スポンサーリンク

概要

• 論文の詳細を見る

• This experiment was conducted to examine hemorrhagic acute anemia effects on wound healing, in particular the influence of serum transfusion. Rabbits weighing 900 to 1, 100g were the subjects. Open wounds of 1cm in diameter was produced on the back skin for examining reduction of the wounded area, mean duration of wound healing, histological findings and mitotic index.<BR>The subjects were divided into 3 groups: acute anemia group (Bleeding of 25m<I>l</I>/kg body weight), serum transfusion group (after the collection of blood, serum separated from blood was transfused), and non-bleeding control group.<BR>All groups showed a similar course of reduction in the wounded areas, but differed in period of rapid reduction in the wounded areas. In control and serum transfusion groups, the period was between the 7th day and 9th day, whereas it was between 8th to 10th day in acute anemia group.<BR>The mean durations of wound healing were for 10.75 days in control group, 10.95 days in serum transfusion group, and 12.10 days in acute anemia group.<BR>Histological findings revealed that wound healing was delayed 1 or 2 days in the acute anemia group when compared to control and serum transfusion groups. The mitotic index showed maximum on the 2nd day, gradually decreased from the 4th day and returned to normal range on the 10th day in control group. In the serum transfusion group, maximum level was obtained on the 4th day, gradually decreased from the 5th day, and returned to normal range on the 10th day. On the other hand, the acute anemia group maximum level was obtained on the 2nd day but the level was lower than that of control or serum transfusion groups, and decreased gradually from the 6th day but did not return to normal range on the 10th day.<BR>Hemorrhagic acute anemia induced delay of wound healing, which was markedly improved by treatment with serum transfusion.

• 社団法人 日本口腔外科学会の論文

著者

• 久野 均

  愛知学院大学歯学部第1口腔外科学教室

関連論文

• 抜歯後疼痛に対する非ステロイド系消炎鎮痛剤Fenoprofenの鎮痛効果 : 二重盲検試験による臨床評価
• 石灰化歯原性嚢胞の2症例
• Skin inlay graftを用いた口腔癌切除後の即時再建
• 顔面非対称を伴う左側下顎頭肥大の1例
• 下顎部にみられたamelanotic melanomaの1例
• 基底細胞母斑症候群の1例
• The effect of hemorrhagic acute anemia on wound healing. Influence of serum transfusion.:Influence of serum transfusion
• タイトル無し

スポンサーリンク