STUDIES ON THE INDUSTRIAL PRODUCTION OF FLAVIN-ADENINE DINUCLEOTIDE:I. PREPARATION OF MYCELIUM OF EREMOTHECIUM ASHBYII AS A RAW MATERIAL CONTAINING FLAVIN-ADENINE DINUCLEOTIDE

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概要

• 論文の詳細を見る

• In order to prepare the mycelia of Er. ashbyii as a raw material for extracting FAD, some basal cultural conditions were examined. In these experiments, the FAD stored in the mycelia amounted to 60-120mg/l, and the highest yield obtained was 194mg/l, whereby a shaking culture was used with a medium containing 1% glucose, 1.5% peptone, and 0.1% CSL and incubated for 72hr. In general, with the rise in mycelial growth, the FAD production in the mycelia seems to be decreased.Preparation of dry mycelia was tested by 3 methods including dehydration with dry acetone and drying by heat. Loss of FAD amounted to about 30% of the initial values. However, the FAD in dried mycelial preparations was stable at least for 6 months in a desiccator. The results of cultures in a 2-ton fermentor were also reported.

• 日本ビタミン学会の論文

著者

• IZUMIYA MASAKAZU

  Wakamoto Pharmaceutical Co., Ltd.

• TSUKIHARA KAZUNORI

  Wakamoto Pharmaceutical Co., Ltd.

• MINOURA KYUBEI

  Wakamoto Pharmaceutical Co., Ltd.

関連論文

• STUDIES ON THE INDUSTRIAL PRODUCTION OF FLAVIN-ADENINE DINUCLEOTIDE:I. PREPARATION OF MYCELIUM OF EREMOTHECIUM ASHBYII AS A RAW MATERIAL CONTAINING FLAVIN-ADENINE DINUCLEOTIDE

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